Hypersensitivity reactions (serious allergic reaction).Some patients may require an additional dose of Praxbind. Recurrence of bleeding and increase in coagulation parameters.Your doctor will resume Pradaxa as soon as medically appropriate. Pradaxa treatment can be initiated 24 hours after administration of Praxbind. Blood clots. Praxbind reverses Pradaxa so patients are at exposed to the thrombotic risk (blood clots) of the underlying disease that Pradaxa is being given for.« Click here to return to The MTM Review.Serious side effects have been reported with Praxbind including the following: Jennings added that, since about 1% to 4% of users are likely to experience major bleeding episodes and another 1% of the group is likely to undergo emergency surgery, as many as 500,000 patients will require, within 5 years, drugs that can rapidly reverse anticoagulation. Jennings estimated that 23 million to 36 million patients in the developed world could be using the new anticoagulants by 2020. The special presentation, which occurred before the FDA approval of Praxbind was announced, was led by Lisa Jennings, PhD, professor and director of the Vascular Biology Center at the University of Tennessee Health Science Center in Memphis. A presentation recently at the annual Transcatheter Cardiovascular Therapeutics meeting suggested that the approval of reversal agents could increase use of the new anticoagulants for stroke prevention in patients with atrial fibrillation. Washington, DC-The FDA recently accelerated approval of an agent, Praxbind (idarucizumab), to reverse Pradaxa’s blood-thinning effects in an emergency situation.

Praxbind fda approval